Tolerance breaks & the pharmacokinetics of cannabis

filefish

Member
OK so everyone knows approximately how tolerance works through their own experiences. But what I've been wondering is is there any hard data/studies or anything quantitative about how fast cannabis tolerance builds up and how fast it drops upon cessation of use? I guess what specifically they'd be looking at is how the CB receptors density changes and how or if that relates to the THC storage in the body. I've never found anything about it.

I always think about this kind of thing when starting t-breaks.
 
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