I love my ez cloners, though diy clone machines will do the same thing.
The biggest issues I've had with the clone machines is sterility, which lead to always having to replace collars and the clogged spray nozzles (roots) on the manifold.
The last few years been using permaclone collars, the kind you can sanitize in a goose bag in the microwave. Expensive up front but they pay for themselves after a couple runs, they've rooted at least a couple thousand with same collars, sometimes I double and triple up cuts per collar.
I never change my water in a clone cycle, only adding more to top off as they root and start to drink. Depending on need/schedule I will transplant as soon as rooted or let grow some wizard beards in the machine.
In the cloner I only use base nutes at same ppm of the moms, kln hormone, and a clear rez knockoff (
https://www.rollitup.org/t/make-2200-worth-of-clear-rez-for-4.423650/). I see roots in as little as 10 days but most of the time I won't even check them for 2-3 wks.
Temps can be an issue for some, my 60 site I run on a chiller, but you can keep the slime away by adding clear rez equivalent up to every 3 days. I've tried 15on/15off on the sprayer manifold which works to keep temps lower, however have had pumps decide to not turn on so I just run the pumps 24/7.
I keep the lights over the clone machines off for the first few days, which helps keep the clones from yellowing. I have used the vitagrow anti-wilt in the past but find it unnecessary if the environment is ideal.
Used to be a domer with rapids or rockwool but once I got the cloners down to set-and-forget I haven't looked back.