Am I running out of room?

I have six plants between 20-26" each, in a room approx. 4X5' in 6 gallon pots which take quite a bit of room. The plants are in flower( almost 2 weeks) and getting very bushy. They are starting to run into the walls and each other. My question is, would I be better off getting rid of a couple to make more room for the the others or should I just let them go as is till the end. Is there a general rule on this? They are skunk strain and I am told they get pretty big? this is my first grow so I really don,t know....Thanks anyone