As in is that area salvageable? Anything with rot is immediately garbage and unhealthy. As for all your options, definitely remove but how much and how far around it to trim is the question, because not all spores are visible. It's just the concentrated areas that are visible.
Now thinking off the top of my head, I'd researched about hydrogen peroxide baths if you're harvesting. I wonder if you could mix the same ratio in a spray bottle and spray the surrounding nugs for a foamy reaction
![Confused :confused: :confused:](/styles/smilies/confused.png)