Mounting the scrubber entirely inside the grow has me wondering in terms of your proposed sealed setup. I've been noting that most people seem to have their filters inside, pulling exhaust out through them. While there's really no better way to do it with a conventional setup requiring air exchange, I keep thinking that this positioning of the filter might remove more of the terpenes from the buds than would be ideal. Running a scrubber in a sealed environment w/o any exhaust would seems like it could accelerate that process--especially if the scrubber is always kept running when setup entirely inside the grow, where it might not be in a setup in which it is attached to an exhaust.
I like stinky pot, just not a stinky apartment, you know?
So rather than replicating the conventional setup inside a sealed compartment, why not mount the scrubbers outside of the flowering chamber (if practical, given room volume, cost, and CFM/dB ratings)? If the chamber is still going to have an exhaust (even if infrequently used) you'll still need to filter it, so this would be an "in addition to" rather than "instead of" but might give better results. You would run the scrubbers outside the chamber full time and the one inside would only ever come into play when the exhaust fan runs.
So far as your more general question on environmental control and what LoudBlunts had to say, I tend to agree with you Puffin. He came on rather strong, and his opinion seems to be based more on inherited folk wisdom than botany. There are a good number of conflicting 'rules of thumb' in growing, usually because they're intended for different contexts or setups. Fresh air exchange is recommended by default, but it isn't truly a requirement as long as you're making sure that the roots get O2 and the leaves transpire during photosynthesis (cheap oscillating fan and good humidity control will do the trick there).
And as you said, a sealed space is actually beneficial in avoiding infestations, etc, provided--again--that you can keep it at the right temps, humidity, etc to avoid other problems.
So, what you're describing *should* work, though practically speaking it will require you to spend more time and money to effectively manage temps, humidity and odor. And tolerances will be more narrow and drift more rapid than a 'standard' setup.
And on that topic, maybe I need to go back and look at your grow dimensions again, but it sounded smallish. Keep in mind that a 1000W might overly warm a smaller space w/o air circulation even with a cooled hood and good reflectivity. Air cooling the hood keeps the fixture itself from getting hot and radiating heat like a heat sink, but just running the light for long enough may demand at least a periodic air exchange to keep temps down and effectively restore or remove humidity (depending on your ambient atmosphere, I think you said your location required a *de*humidifier.)
So, the easiest answer would be to get a combo fan/dehumidifier/co2 controlling thermo/humidistat/co2 meter that will turn on the fans over a certain temperature point, release co2 when below a certain point (as long as the fan is off) and monitor humidity, turning the dehumidifer on/off and/or running the fans as required. Basically, greenhouse equipment. Hard to buy discretely but takes the guess-work out.
Something like this:
Simply Hydroponics & Organics - AIR-4 Atmospheric
Not cheap, though.
Anyway, it's a good concept. If you do this, please consider journaling it--I'd like to see how it goes.