Really depends on whether your medibles are Sativa based or Indica based. Also depends on *when* the bud was harvested. Most experienced growers on this site know the color of the trichomes(clear, cloudy or amber) largely determines the kind of *buzz* you will feel. My medibles are fairly potent and can make your legs feel like rubber. Mine are also Indica based, and that's indicative (pun. lol) of a heavy hitting indica anyways. Takes about 45 mins to an hr before they kick in, but when they do it's about a 3-4 hour ride easy.