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Saerimmner

Well-Known Member
Todays read for you all lol

What Happens To Your Body When You Get Drunk And Stoned At The Same Time?

The science of the spins


By
Gabe Bergado
Posted 03.21.2014 at 3:08 pm 1.2K

Let's Get Weird
Flickr, L.C.Nøttaasen and Stephen Stills; Modified by Gabe Bergado
The intoxicating effects of alcohol and of marijuana have been widely studied, but their combined effect—getting "cross-faded"—is woefully underexplored scientific territory. Here's a look at what we know about how pot and booze together affect the brain.

First, the basics: Marijuana contains THC (tetrahydrocannabinol), which acts on the brain's cannabinoid receptors. Alcohol depresses the central nervous system. Trying to compare the two isn't even like comparing apples and oranges, says Gary Wenk, a professor of psychology and neuroscience at Ohio State University. "It's apples and vegetables. They're very different drugs." An extremely simplified explanation would be to say that THC largely has cognitive effects, like paranoia and a distorted sense of time, while alcohol mainly affects motor skills, making it hard to walk in a straight line and causing slurred speech.

After individuals drank a large dose of alcohol, the THC levels in their blood plasma nearly doubled.
So does combining weed and alcohol just add their respective effects together? Not quite, says Scott Lukas, who teaches at Harvard Medical School and has researched the interaction of various drugs. In a study published in 2001, Lukas found that after individuals smoked marijuana and a drank large dose of alcohol, the equivalent to a couple of shots, the THC levels in their blood plasma nearly doubled compared with people who smoked pot and consumed a placebo drink. The buzzed people in the study also detected the effects of marijuana sooner than those who only got stoned, and rated their high as subjectively "better." This suggests that getting boozed up causes more THC to reach the brain, via the bloodstream, within the first few minutes of ingestion. One explanation for this finding is that alcohol may cause changes in blood vessels that boost the absorption of inhaled THC.

Lukas isn't worried that the combination could be lethal, but he says that getting cross-faded could be more risky that just getting drunk or high alone. With more THC hitting the brain thanks to the ethanol in alcoholic drinks, the usual effects of marijuana—like impaired judgment and increased heart rate—are stronger. Which means accidents like drownings and car crashes could be more likely, Lukas says. He also points out that the amounts of drugs approved for his research were lower than the levels that people often use while out partying.

More recently, a study from Duke University found that adolescent rats under the influence of ethanol and THC were less likely to explore than those under the influence of either ethanol or THC alone. The same study also found that adult rats given the ethanol/THC combination had more trouble remembering new objects compared with adult rats given either drug alone.

Further research is needed on the additive effects of munchies and drunchies.
 

tip top toker

Well-Known Member
Todays read for you all lol

What Happens To Your Body When You Get Drunk And Stoned At The Same Time?

The science of the spins

By
Gabe Bergado
Posted 03.21.2014 at 3:08 pm 1.2K

Let's Get Weird
Flickr, L.C.Nøttaasen and Stephen Stills; Modified by Gabe Bergado
The intoxicating effects of alcohol and of marijuana have been widely studied, but their combined effect—getting "cross-faded"—is woefully underexplored scientific territory. Here's a look at what we know about how pot and booze together affect the brain.

First, the basics: Marijuana contains THC (tetrahydrocannabinol), which acts on the brain's cannabinoid receptors. Alcohol depresses the central nervous system. Trying to compare the two isn't even like comparing apples and oranges, says Gary Wenk, a professor of psychology and neuroscience at Ohio State University. "It's apples and vegetables. They're very different drugs." An extremely simplified explanation would be to say that THC largely has cognitive effects, like paranoia and a distorted sense of time, while alcohol mainly affects motor skills, making it hard to walk in a straight line and causing slurred speech.

After individuals drank a large dose of alcohol, the THC levels in their blood plasma nearly doubled.
So does combining weed and alcohol just add their respective effects together? Not quite, says Scott Lukas, who teaches at Harvard Medical School and has researched the interaction of various drugs. In a study published in 2001, Lukas found that after individuals smoked marijuana and a drank large dose of alcohol, the equivalent to a couple of shots, the THC levels in their blood plasma nearly doubled compared with people who smoked pot and consumed a placebo drink. The buzzed people in the study also detected the effects of marijuana sooner than those who only got stoned, and rated their high as subjectively "better." This suggests that getting boozed up causes more THC to reach the brain, via the bloodstream, within the first few minutes of ingestion. One explanation for this finding is that alcohol may cause changes in blood vessels that boost the absorption of inhaled THC.

Lukas isn't worried that the combination could be lethal, but he says that getting cross-faded could be more risky that just getting drunk or high alone. With more THC hitting the brain thanks to the ethanol in alcoholic drinks, the usual effects of marijuana—like impaired judgment and increased heart rate—are stronger. Which means accidents like drownings and car crashes could be more likely, Lukas says. He also points out that the amounts of drugs approved for his research were lower than the levels that people often use while out partying.

More recently, a study from Duke University found that adolescent rats under the influence of ethanol and THC were less likely to explore than those under the influence of either ethanol or THC alone. The same study also found that adult rats given the ethanol/THC combination had more trouble remembering new objects compared with adult rats given either drug alone.

Further research is needed on the additive effects of munchies and drunchies.
Interesting read. Other than with the gf who doesn't really drink, i can't recall the last time i was sat at home with a joint not having my fridge full of booze :)
 

tip top toker

Well-Known Member
Just caught a glimpse of yet another Scottish referendum article. I cannot wait for the date. I couldn't personally care what happens, that's for the Scots to decide, but as it is, i'm loving it. I wonder what it is about scotland that Mr Cameron is really concerned about, because from all indications, he's shitting bricks over the notion of the leaving.

Dear diary. This year I was so shit at my job that I lost an entire country after they told me to fuck myself.
 

Saerimmner

Well-Known Member
Just caught a glimpse of yet another Scottish referendum article. I cannot wait for the date. I couldn't personally care what happens, that's for the Scots to decide, but as it is, i'm loving it. I wonder what it is about scotland that Mr Cameron is really concerned about, because from all indications, he's shitting bricks over the notion of the leaving. Look at that cameron et al, you're doing such a shit job that scotland won't just vote differently next election, they'll just vote never to have to put up with you again :D
Its all to do with gas supplies/reserves and the amount of money they would have to give scotland as part of the split for various things like roads/welfare/schools etc
 

tip top toker

Well-Known Member
And re-locate trident, and take on the 3140bn of scotlands debt, and yes. It's all fairly obvious. Yet Cameron pretends it's not and keeps harping on about how we're better together. Clearly scotland has an idea that this isn't true :D

But i think all these non-scot celebrities donating millions of pounds to the No campaign should be chucked in prison. It's fuck all to do with you, get over it.
 

Saerimmner

Well-Known Member
And re-locate trident, and take on the 3140bn of scotlands debt, and yes. It's all fairly obvious. Yet Cameron pretends it's not and keeps harping on about how we're better together. Clearly scotland has an idea that this isn't true :D

But i think all these non-scot celebrities donating millions of pounds to the No campaign should be chucked in prison. It's fuck all to do with you, get over it.
a lot of them have vested business interests in what happens re: the split, they stand to lose a lot of money if scotland go solo
 

zeddd

Well-Known Member
indepedence from whom? the whole thing is utter bollox, so they want to keep the pound, therefore they have a central bank in england, but will be more allied to the EU which is a supranational neo marxist outfit with unelected technocrats placed there by central banks...there is no independence for scotland just a shift to another system of debt slavery
 

tip top toker

Well-Known Member
a lot of them have vested business interests in what happens re: the split, they stand to lose a lot of money if scotland go solo
Like J.k rowling? And it till has nothing to do with them the referendum is about scotland for scotland, not some rich bitch with a vested interest.
 

Saerimmner

Well-Known Member
indepedence from whom? the whole thing is utter bollox, so they want to keep the pound, therefore they have a central bank in england, but will be more allied to the EU which is a supranational neo marxist outfit with unelected technocrats placed there by central banks...there is no independence for scotland just a shift to another system of debt slavery
let me guess...jews again?
 

R3l@X

Well-Known Member
Yeh have you sampled this Irish lads hash.is it soft or hard stuff
Not his hash,his green an oz of the stuff I've ordered is 250e n I'll know Tuesday for sure. Blossoms from India I'm weird about ordering from India...selector is more pricy but next day delivery n not having to worry about customs makes it worth it...well I'll know once I try ir
 

Ishrahnai

Well-Known Member
Had a few vals an hour ago just had to have me last FAT line of BW's gear shit proper makes ya gag when it goin down...I'm on a nice even level tho l..thank fook foe auto correct lmao
Sounds like your having a better Sunday than I am. Still, spent the avo on the beach. Roast, rum and reefer will do just fine.
 
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