Pandemic 2020

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mysunnyboy

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Visit dad after the new year, when you've both been inoculated, fuck knows how many people are gonna kill their parents and grandparents this Thanksgiving and Christmas. We are only weeks away from vaccine deployment and that will be the real tragedy, this winter will take many, stupidity will take more.

If you are vulnerable or elderly you will be among the first to be offered inoculation and both of you might be good to go by the end of February, it will be over for you then.
I’m super vulnerable and I’m not too sure about taking it right away.
I would never buy a first year car. I know this is different but no one knows what covid may really do to us long term.
I’m not worried about the drug itself, just Covid 19. Shit my buddy worked on the Pfizer vaccine so I do trust it.
I just don’t want to get any sicker than I already am, you know.
 

DIY-HP-LED

Well-Known Member
I’m super vulnerable and I’m not too sure about taking it right away.
I would never buy a first year car. I know this is different but no one knows what covid may really do to us long term.
I’m not worried about the drug itself, just Covid 19. Shit my buddy worked on the Pfizer vaccine so I do trust it.
I just don’t want to get any sicker than I already am, you know.
This one comes with a kick and fever, your doctor is your best guide on that one, id seek their counsel. It should be very effective as you know, whether it will trigger an adverse immune reaction and exacerbate RA, it's the doctor's call and yours too, you sound pretty informed.

One good thing about this shit is they have got a way better handle on inflammatory reactions now and I would expect therapeutics to blunt specific immune inflammatory responses, some recent work at St Jude's was important in this regard.
 

mysunnyboy

Well-Known Member
This one comes with a kick and fever, your doctor is your best guide on that one, id seek their counsel. It should be very effective as you know, whether it will trigger an adverse immune reaction and exacerbate RA, it's the doctor's call and yours too, you sound pretty informed.

One good thing about this shit is they have got a way better handle on inflammatory reactions now and I would expect therapeutics to blunt immune specific inflammatory responses, some recent work at St Jude's was important in this regard.
Yeah, biologics haven’t worked for me. I’m pretty screwed. Even the $5000 humira pop didn’t do shit.
But there’s weed!
 

DIY-HP-LED

Well-Known Member
Yeah, biologics haven’t worked for me. I’m pretty screwed. Even the $5000 humira pop didn’t do shit.
But there’s weed!
There are two was out of suffering for you Science (therapeutics) and MBSR, I'd recommend and 8 week evidence based program near you, your insurance might even pay for it. If smoking dope does not affect you too much and you are an older adult the two are not mutually exclusive. Pain is the inevitable result of the human condition, but we can have a choice when it comes to suffering, it takes training, but not as long as you might think. Do it with your partner, something to do together, here is a short video by my favorite fellow Buddhist geek, it's very much a female thing too.

This is not the whole story but a salient part for you, 8 weeks to change your world and make you happier for sure.

What Science Can Teach Us About Practice
 

mysunnyboy

Well-Known Member
There are two was out of suffering for you Science (therapeutics) and MBSR, I'd recommend and 8 week evidence based program near you, your insurance might even pay for it. If smoking dope does not affect you too much and you are an older adult the two are not mutually exclusive. Pain is the inevitable result of the human condition, but we can have a choice when it comes to suffering, it takes training, but not as long as you might think. Do it with your partner, something to do together, here is a short video by my favorite fellow Buddhist geek, it's very much a female thing too.

This is not the whole story but a salient part for you, 8 weeks to change your world and make you happier for sure.

What Science Can Teach Us About Practice
Uh what?
I’m 54. RA, Palindromic Arthritis, Osteoarthritis, MCTD, Fibromyalgia, Lupus (thanks Humira), COPD (thanks RA), ILD (RA as well), take steroids every day along with 2 dmards and 12 other scripts.
I smoke the shit out of weed. I can’t walk 20 yards but at least I’m high.
 

mysunnyboy

Well-Known Member
Uh what?
I’m 54. RA, Palindromic Arthritis, Osteoarthritis, MCTD, Fibromyalgia, Lupus (thanks Humira), COPD (thanks RA), ILD (RA as well), take steroids every day along with 2 dmards and 12 other scripts.
I smoke the shit out of weed. I can’t walk 20 yards but at least I’m high.
Oh yeah and my arm is shattered and my hands are always on fire.
I don’t chant but I can disassociate just fine :eyesmoke:
 

DIY-HP-LED

Well-Known Member
Uh what?
I’m 54. RA, Palindromic Arthritis, Osteoarthritis, MCTD, Fibromyalgia, Lupus (thanks Humira), COPD (thanks RA), ILD (RA as well), take steroids every day along with 2 dmards and 12 other scripts.
I smoke the shit out of weed. I can’t walk 20 yards but at least I’m high.
Yer tailor made for MBSR, it was designed for people like you and worse, though lots of other people take the course too for a variety of reasons. Many programs are offered in hospitals, to be an MBSR instructor requires a masters level in psych and 5 years experience as a practitioner. Kinda like a physiotherapist, very fulfilling work, you don't burn out, compassion makes ya stronger.
 
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DIY-HP-LED

Well-Known Member

FDA authorizes emergency use of Regeneron antibody treatment given to Trum

The Food and Drug Administration announced Saturday evening it has granted emergency use authorization for Regeneron Pharmaceuticals' antibody cocktail given to President Trump to treat his COVID-19 infection last month.

Why it matters: Regeneron's two monoclonal antibodies, casirivimab and imdevimab, are for people who tested positive for the coronavirus and "who are at high risk for progressing to severe COVID-19," including people who are 65 and older, and/or people with certain chronic illnesses, per an FDA statement.

Of note: "The safety and effectiveness of this investigational therapy for use in the treatment of COVID-19 continues to be evaluated," the FDA said.

  • "Casirivimab and imdevimab are not authorized for patients who are hospitalized due to COVID-19 or require oxygen therapy due to COVID-19."
Driving the news: A clinical trial of patients with COVID-19 found that when the two antibodies were administered together, they "were shown to reduce COVID-19-related hospitalization or emergency room visits in patients at high risk for disease progression within 28 days after treatment when compared to placebo," the FDA said.

  • Regeneron president and chief scientific officer George Yancopoulos said in a statement this trial of roughly 800 non-hospitalized patients "showed significant reductions in virus levels within days" of receiving the treatment, called REGEN-COV2, "which were associated with significantly fewer medical visits."
What to expect: Regeneron expects to have doses of REGEN-COV2 ready for some 80,000 patients by the end of November, about 200,000 patients by the first week of January, and approximately 300,000 patients in total by the end of January 2021.

For the record: The FDA issued a similar emergency use authorization for Eli Lilly's antibody therapy, bamlanivimab, earlier this month.

Go deeper: Regeneron CEO: Trump's success with antibody cocktail is not evidence of cure
 

DIY-HP-LED

Well-Known Member

Moderna to charge $25-$37 for COVID-19 vaccine: CEO tells paper

FRANKFURT (Reuters) - Moderna will charge governments between $25 and $37 per dose of its COVID-19 vaccine candidate, depending on the amount ordered, Chief Executive Stephane Bancel told German weekly Welt am Sonntag (WamS).

“Our vaccine therefore costs about the same as a flu shot, which is between $10 and $50,” he was quoted as saying.

On Monday, an EU official involved in the talks said the European Commission wanted to reach a deal with Moderna for the supply of millions of doses of its vaccine candidate for a price below $25 per dose.

“Nothing is signed yet, but we’re close to a deal with the EU Commission. We want to deliver to Europe and are in constructive talks,” Bancel told WamS, adding it was just a “matter of days” until a contract would be ready.

Moderna has said its experimental vaccine is 94.5% effective in preventing COVID-19, based on interim data from a late-stage clinical trial, becoming the second developer to report results that far exceeded expectations after Pfizer and its partner BioNTech.

The EU has been in talks with Moderna for its experimental COVID-19 vaccine at least since July.
 

DIY-HP-LED

Well-Known Member
Maybe Donald skipped the meeting because he didn't want to associate himself with this and tarnish his reputation..
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G20 leaders pledge to fund fair distribution of COVID-19 vaccines
'We recognize the role of extensive immunization as a global public good'

Leaders of the world's 20 biggest economies on Sunday will pledge to pay for a fair distribution of COVID-19 vaccines, drugs and tests around the world so that poorer countries are not left out and to extend debt relief to them, a draft G20 communique showed.

"We will spare no effort to ensure their affordable and equitable access for all people, consistent with members' commitments to incentivize innovation," the leaders said in the draft G20 statement, seen by Reuters. "We recognize the role of extensive immunization as a global public good."

The draft also calls on private creditors to join the debt-servicing moratorium, which the G20 wants to extend until the middle of 2021 and possibly longer, and endorses a common framework for dealing with debt issues beyond that.

"There is a lack of participation from private creditors, and we strongly encourage them to participate on comparable terms when requested by eligible countries," it said.
The leaders also recognized the specific challenges faced by countries in Africa and small island developing states, reflecting growing recognition that even some middle-income countries may need debt relief as a result of the pandemic.

Keen to be better prepared for any potential pandemic that might come, G20 leaders also said they would commit "to advancing global pandemic preparedness, prevention, detection and response" and "to the continued sharing of timely, transparent and standardized data and information."

The leaders attending the virtual summit, hosted by Saudi Arabia, said the global economy was starting to pick up, but the recovery remained "uneven, highly uncertain and subject to elevated downside risks."

The leaders pledged to continue to use all available policy tools as long as needed to safeguard lives, jobs and incomes, and they encouraged the multilateral development banks to strengthen their efforts to help countries deal with the crisis.

The European Union has called for $4.5 billion US by the end of the year from the G20 to pay for COVID-19 fighting tools for poorer countries.
 

DIY-HP-LED

Well-Known Member
Oh yeah and my arm is shattered and my hands are always on fire.
I don’t chant but I can disassociate just fine :eyesmoke:
I've selected a guru for you, you can thank Jesus she became a Buddhist nun and not a Catholic one! She musta went through men like shit through a goose, tongue like a razor.

You might like the personality and imagine what she would be like if she never meditated! A great no shit teacher, this is the traditional method, or one of them. Tons of her videos online, a character, used to watch her back in the day.
Be Your Own Therapist
 

DIY-HP-LED

Well-Known Member
We have Thanksgiving earlier in Canada and guess what happened to covid cases? Read and heed.
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Will the U.S. heed Canada's Thanksgiving lesson?
Canada's staring down a Covid surge that has been blamed on social gatherings. And as Americans contemplate their holiday plans, Canadians are desperately trying to save Christmas.

The war on Christmas has come for Thanksgiving, with U.S. health officials warning against holiday travel as Canada serves as a cautionary tale of what happens when families get together in a pandemic.

Six weeks after Canada’s Thanksgiving, the Covid-19 crisis is hitting a break-glass moment in the nation of 37 million after holiday gatherings appeared to catalyze the spread of the coronavirus. Canada has gone from diagnosing more than 2,000 cases per day in mid-October to an average of 4,776 cases daily in the past week, according to Public Health Agency of Canada modeling released Friday.

Few Canadians fly to grandma’s house for a turkey dinner, so the spike there could offer just a taste of the pain Americans could see after next week’s holiday — usually preceded by the biggest travel day of the year in the U.S.

Health experts are desperately warning Americans not to fly, train or drive to see family and say that absent changes to Americans' typical holiday season behavior, a traditional Thanksgiving dinner could lead to thousands more funerals by Christmas.

More than 250,000 Americans have died from the disease since March. Canada had kept the pandemic in check compared with its neighbor to the south, but the new surge has officials there sounding caution as well.

An urgent warning against travel came this week from the U.S. Centers for Disease Control and Prevention after more than a million new Covid cases were recorded over seven days. Some governors and state officials have been even more blunt: stay home.

"What's at stake is basically the increased chance of one of your loved ones becoming sick and being hospitalized and dying," said Dr. Henry Walke, the CDC’s Covid-19 incident manager. "And around these holidays, we tend to get people together from multiple generations."

AAA forecasts Thanksgiving travel to drop at least 10 percent from 2019 — the biggest one-year decline since the 2008 recession — but notes that CDC and state guidance will likely convince even more prospective travelers to stay home. Still, the high end of that forecast is 50 million Americans hopping in cars or onto planes to sit down to tables with all the trimmings.

So while some Americans are planning for Zoomsgiving, Canadians are dealing with a post-Thanksgiving surge. And now, talk about Christmas is dire.

New public health modeling projects that Canada could see up to 60,000 new cases of Covid per day — more than a dozen times current levels — by the end of December if people increase their contacts and celebrate the holidays as normal. Even the status quo for Canadians would translate to more than 20,000 new cases daily, according to the projections, or about five times higher than today. The runaway numbers have been attributed in part to Thanksgiving gatherings.

Trudeau implored Canadians on Friday to stay home and avoid traveling if they can. "In the coming weeks, we need to flatten this curve," he said.

The comments were a significant change in tone for the prime minister who suggested to Canadians throughout the fall that they had "a shot at Christmas," provided they hunker down. "We all want to try and have as normal a Christmas as possible even though a normal Christmas is, quite frankly, right out of the question," Trudeau said Friday.

Provincial premiers have been reluctant to reimpose the stark measures from the spring on their residents for fear of further damaging economies. Still, some have flirted with greater restrictions as cases continue to mount — Ontario just announced new lockdowns in hot spots, and Quebec has a plan to allow gatherings of up to 10 people for four days around Christmas while imploring residents to self-quarantine for a week before and after the events.

Throughout the U.S., governors are increasingly instituting limits on public and private gatherings and testing and quarantine requirements for those who choose to travel out of state.
 
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DIY-HP-LED

Well-Known Member
Confidence in the 2 new vaccines is growing fast, we will see how many really think it's a hoax soon.
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Why coronavirus vaccine polling numbers are mostly good news

(CNN)Poll of the week: A new Gallup poll finds that 58% of Americans said they would get vaccinated against the coronavirus if there was an FDA-approved vaccine available right now at no cost.

That's up from mid-September when just 50% said they would get vaccinated.

What's the point: There's been mostly good news on the coronavirus vaccine front. Two separate vaccine makers (Moderna and Pfizer) say their vaccines are about 95% effective with no major safety concerns, and Pfizer has applied to the Food and Drug Administration for emergency authorization. The hope is that many people can begin to get immunized by April, according to the National Institutes of Health Director Dr. Francis Collins.

A vaccine at this high efficiency could be a game changer.

A vaccine, however, isn't worth much if Americans won't actually get it. A look at the polling trendline on a coronavirus vaccine and history suggests it is, again, mostly good news when it comes to people being willing to get it.

As the Gallup data reveals, folks are more willing to get the vaccine than were a few months ago. We see a similar trend in the data from the Axios/Ipsos poll. In a slightly different question, 45% of Americans say they are likely to immediately be vaccinated as soon as possible. That's up from 38% in September.

When you dig deeper, you see that much of the concern with a vaccine has to do with safety and efficiency. In the Axios/Ipsos poll, 68% of Americans said they'd likely get the vaccine if proven safe and effective by public health officials. Among the 42% of Americans who said they wouldn't take the vaccination in the Gallup poll, 63% cited either a rushed timeline or waiting to see if it's safe as the reason.

In other words, a lot of folks just want to know that the vaccine is safe and effective. If it is, the percentage of folks willing to get vaccinated is likely to climb.

Just the latest news on Pfizer and Moderna vaccines could boost the percentage willing to get the vaccination.
In the Axios/Ipsos poll conducted before Moderna's released their initial findings and after Pfizer's initial findings (but before they released more details and asked for emergency authorization), 61% of Americans said they'd take the vaccine if the pharmaceutical companies told them it was at least 90% effective. This up from the 45% baseline who said they'd get immediately vaccinated without knowing any more information in the same poll. The two companies have now said their vaccines were 94.5% and 95% effective.

If 70% of the population got the vaccine, it could be huge in defeating the virus. A vaccine that covers 65% to 70% of the population is likely to get us population immunity through vaccination, according to the World Health Organization.
A look at the public opinion as Jonas Salk's polio vaccine was being tested indicates more potential good news. In an almost identical finding to Gallup's most recent poll on coronavirus, 60% of those who had heard about the polio vaccine told Gallup in May 1954 that they would take it. A similar percentage said they'd have their children get it.

Once the vaccine was shown to be effective, the necessary number of Americans got the vaccine.

The polio vaccine ended up being one of the most successful vaccination programs in world history. Within a few years, the number of new cases a year fell from 15,000 to 100. America was able to knock out what once was one of the worst epidemics in its history, and no cases have originated in the country for more than 40 years.

Now, we obviously don't know how the coronavirus vaccines will turn out. History is only a guide.

Perhaps the most important variable to watch over the next few months is a partisan divide on coronavirus vaccinations. Right now, there isn't much of one. In Gallup's poll, 69% of Democrats and 49% of Republicans said they would get vaccinated against the coronavirus if there was an FDA-approved vaccine available right now at no cost. We get closer to 90-point gaps on how Democrats and Republicans vote for president.

Hopefully, the vaccine uptake is bipartisan when the vaccine hits the market. A lot of lives could depend on it.
This is why it's so important for both Democratic and Republican leaders to back up the scientists if they say a vaccination is safe.
 

Fogdog

Well-Known Member
Just a note from Oregon regarding the seriousness with which we are taking the recent spike in new cases.

Drove over to the coast yesterday with the family. Beautiful day. Sun out, light breeze, cool but not uncomfortably so.

Lots of people out enjoying the day. Kayaks on the bay, surfers along the coast, dogs running on the beach unleashed, people out strolling and talking. No masks evident. Not much effort at social distancing. People were just having a good old time as if the epidemic weren't spreading rapidly.

We ate lunch in the car. Did not go for a walk on the beach as planned. We headed inland where we could hike in the woods without being exposed to the virus by idiots.

We are so fucked right now.

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