I've been studying chemistry for a while now, and I honestly believe most of my instructors probably couldn't handle LSD synthesis. That is, without a very, very detailed guide. I've read through lots of research articles regarding the synthesis and the process isn't that bad. In theory, anyway. Most anecdotal reports suggest if you try it, well, it's gonna be a real bitch. Everything must be perfect; not just good, or even really, really good, it has to be perfect. You can do everything right (or so you think) and for some unknown reason, it just won't work; leading to the destruction of expensive and hard to come by reagents. I'm not sure where the problem lies exactly, but it seems that except for chemists who've actually been walked through it by someone who's successfully done it on multiple occaisons, it's something best let alone. Don't let me discourage you, but most of us lack the lab space/equipment/financial resources/connections to suppliers to have any hope of completeing a successful job of it. Well, having said that, good luck.