decent cost of living is an independent viewpoint - better then NYC, YES!!! better then eastern WA? not really. it's all relative. Jobs? again, relative viewpoint to what you do? CEO? not really. IT career, not bad. do some research via job sites to see how broad or narrow your field is for hiring. at the same time notate salaries. this will give you a rough idea if comparible to your area and 'livable'.
I'm in the Denver-Boulder corridor, not familiar with other areas =\ but I rent a 2br house in good 'hood for $1K/m. No matter where you decide, check the lease!!! I noticed too late that mine says 'no manufacturing of controlled substances, including medical marijuana'. so no home grow for me.
I assume you have read the CO MMJ Laws and have a condition warranting a state license. keep in mind that as a CO MMJ Patient, you are allowed 6 plants growing by default (can be more if the Dr specifically writes the # on your registration/certification that is submitted to the state) ... this is enough to grow/complete 2 girls per month on a rotating basis (clones are easy to come by) .... this will greatly reduce your overall out of pocket expenses for medication as well.