The very best weed is organic, and the very best place to grow is in N. California, the Emerald Triangle. Humboldt, Trinity, Mendocino counties, all you have to do is buy lots of land and you can make it big. $2,000-$5,000 per acre in very rural Humboldt. I know a guy selling 200 acres, with Klamath River access too. Only $400K.
The key to making money is Export to illegal states, you will have to get a network of people put together to make this happen. Logistics.