Just found something while reading that may turn me off Sativas

M

monkeybones

Well-Known Member
You know, ever since i started growing and using this site, I would always read about how sativas are much better of a mind high, and indicas would give you a heavy body high and couch-lock

so, like many other people, i ordered a sativa dominant strain to start off with and never really even tried a plain indica

and like some others, to me pot is just how i feel normal after years of consumption. it kind of lost the ability to make me tremble with joy or anticipation.

these days, i just smoke 8-12 bowls over a 16 hour time period (straight up sativa, of course), and live a pretty normal life. the one thing weed does for me 100% of the time now is induce lethargy

so i've been reading on wikipedia and i'm interested in whether my CB1 receptor has gone neglected for a while.






Tetrahydrocannabivarin

Tetrahydrocannabivarin (THCV, THV) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain. This terpeno-phenolic compound is found naturally in Cannabis, sometimes in significant amounts. The psychoactive effects of THCV in Cannabis preparations are not well characterized.

Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]

THCV has been shown to be a CB1 receptor antagonist, i.e. it blocks the effects of THC.[3]

References

[1] Turner, C.E., Hadley, K.W., and Fetterman, P. 1973. Constituents of Cannabis Sativa L., VI: Propyl Homologues in Samples of Known Geographical Origin. J. Pharm. Sci. 62(10):1739-1741

[2] Hillig, Karl W. and Paul G. Mahlberg. 2004. A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). American Journal of Botany 91(6): 966-975.

[3] Pertwee RG, Thomas A, Stevenson LA, et al. 2007. The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo. Br. J. Pharmacol. 150(5): 586–94.
 
RC7

RC7

Well-Known Member
Well i believe the indicas have the true medicinal value from the CBD and other cannabinoids, but sativas are great for an uplifting high because mental happiness is just as important in life, if not more important. According to this chart THCV does have medicinal value so i believe all cannabinoids serve a purpose. I wouldn't stop smoking sativas if they make you happy and you enjoy it. I would just use indica strains along with the sativa strains so its balanced. Sativas for day, indicas for night. I just took this as you were looking at it from a medicinal stand point... only because most people just smoke for the enjoyment if they don't have medical issues.View attachment 2266871
 
tyler.durden

tyler.durden

Well-Known Member
Do you run just the one Sativa strain, or do you run others, as well? One thing I've found to offset the tolerance you build up is to switch between strains. I'm currently running Trainwreck, white widow, NY-47, OG Kush and NL #5. Like RC7 said, usually my Sativa doms during the day, and the Indica doms at night. Switching between strains daily keeps my high nice and fresh, as well as keeping different clients happy...
 
cannabitch81

cannabitch81

Active Member
monkeybones said:
You know, ever since i started growing and using this site, I would always read about how sativas are much better of a mind high, and indicas would give you a heavy body high and couch-lock

so, like many other people, i ordered a sativa dominant strain to start off with and never really even tried a plain indica

and like some others, to me pot is just how i feel normal after years of consumption. it kind of lost the ability to make me tremble with joy or anticipation.

these days, i just smoke 8-12 bowls over a 16 hour time period (straight up sativa, of course), and live a pretty normal life. the one thing weed does for me 100% of the time now is induce lethargy

so i've been reading on wikipedia and i'm interested in whether my CB1 receptor has gone neglected for a while.






Tetrahydrocannabivarin

Tetrahydrocannabivarin (THCV, THV) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain. This terpeno-phenolic compound is found naturally in Cannabis, sometimes in significant amounts. The psychoactive effects of THCV in Cannabis preparations are not well characterized.

Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]

THCV has been shown to be a CB1 receptor antagonist, i.e. it blocks the effects of THC.[3]

References

[1] Turner, C.E., Hadley, K.W., and Fetterman, P. 1973. Constituents of Cannabis Sativa L., VI: Propyl Homologues in Samples of Known Geographical Origin. J. Pharm. Sci. 62(10):1739-1741

[2] Hillig, Karl W. and Paul G. Mahlberg. 2004. A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). American Journal of Botany 91(6): 966-975.

[3] Pertwee RG, Thomas A, Stevenson LA, et al. 2007. The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo. Br. J. Pharmacol. 150(5): 586–94.
Click to expand...



Where were you when I needed you...LMAO
I needed some help with citations, and obviously you rock at it :)


KEEP TOKIN !!!
 
Grojak

Grojak

Well-Known Member
monkeybones said:
You know, ever since i started growing and using this site, I would always read about how sativas are much better of a mind high, and indicas would give you a heavy body high and couch-lock

so, like many other people, i ordered a sativa dominant strain to start off with and never really even tried a plain indica

and like some others, to me pot is just how i feel normal after years of consumption. it kind of lost the ability to make me tremble with joy or anticipation.

these days, i just smoke 8-12 bowls over a 16 hour time period (straight up sativa, of course), and live a pretty normal life. the one thing weed does for me 100% of the time now is induce lethargy

so i've been reading on wikipedia and i'm interested in whether my CB1 receptor has gone neglected for a while.






Tetrahydrocannabivarin

Tetrahydrocannabivarin (THCV, THV) is a homologue of tetrahydrocannabinol (THC) having a propyl (3-carbon) side chain. This terpeno-phenolic compound is found naturally in Cannabis, sometimes in significant amounts. The psychoactive effects of THCV in Cannabis preparations are not well characterized.

Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]

THCV has been shown to be a CB1 receptor antagonist, i.e. it blocks the effects of THC.[3]

References

[1] Turner, C.E., Hadley, K.W., and Fetterman, P. 1973. Constituents of Cannabis Sativa L., VI: Propyl Homologues in Samples of Known Geographical Origin. J. Pharm. Sci. 62(10):1739-1741

[2] Hillig, Karl W. and Paul G. Mahlberg. 2004. A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae). American Journal of Botany 91(6): 966-975.

[3] Pertwee RG, Thomas A, Stevenson LA, et al. 2007. The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo. Br. J. Pharmacol. 150(5): 586–94.
Click to expand...

LOL you're confused man!!! You're ready to swear off the wrong plant.

Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]"

If this article is true than it is saying that Indica's have high THCV levels and thus could be blocking your CB1 receptor.


There 3/4 subspecies of Marijuana all marijuana is of the species 'Cannabis sativa L' but than you have 3/4 subspecies of the plant these are Sativa, Indica, Ruderalis and in some circles a 4th subspecies being Afghanica, but most refer to the Afghanicas as just plain Indica. So when you read Cannabis sativa L. ssp. indica the SSP stands for subspecies so in horticultural terms you have these: Cannabis sativa L. ssp. sativa, Cannabis sativa L. ssp. indica, Cannabis sativa L. ssp. ruderalis.

I hope you took notes, quiz tomorrow!!!
 
2easy

2easy

Well-Known Member
Grojak said:
LOL you're confused man!!! You're ready to swear off the wrong plant.

Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]"

If this article is true than it is saying that Indica's have high THCV levels and thus could be blocking your CB1 receptor.


There 3/4 subspecies of Marijuana all marijuana is of the species 'Cannabis sativa L' but than you have 3/4 subspecies of the plant these are Sativa, Indica, Ruderalis and in some circles a 4th subspecies being Afghanica, but most refer to the Afghanicas as just plain Indica. So when you read Cannabis sativa L. ssp. indica the SSP stands for subspecies so in horticultural terms you have these: Cannabis sativa L. ssp. sativa, Cannabis sativa L. ssp. indica, Cannabis sativa L. ssp. ruderalis.

I hope you took notes, quiz tomorrow!!!
Click to expand...
this probably explains why i seem to be able to get sooooo much higher smoking sativas than i can smoking indicas
 
M

monkeybones

Well-Known Member
tyler.durden said:
Do you run just the one Sativa strain, or do you run others, as well? One thing I've found to offset the tolerance you build up is to switch between strains. I'm currently running Trainwreck, white widow, NY-47, OG Kush and NL #5. Like RC7 said, usually my Sativa doms during the day, and the Indica doms at night. Switching between strains daily keeps my high nice and fresh, as well as keeping different clients happy...
Click to expand...
i just run one strain at a time, and it's always been a sativa dominant strain. i've always preferred the hybrids though

i want to grow a variety coming up of aurora indica and a sativa dom, and do what tyler.durden and others recommend

it makes perfect logical sense. i am not surprised to notice an imbalanced experience when consuming an disproportionately large amount of sativa
 
M

monkeybones

Well-Known Member
Grojak said:
LOL you're confused man!!! You're ready to swear off the wrong plant.

Plants with elevated levels of propyl cannabinoids (including THCV) have been found in populations of Cannabis sativa L. ssp. indica (= Cannabis indica Lam.) from China, India, Nepal, Thailand, Afghanistan, and Pakistan, as well as southern and western Africa. THCV levels up to 53.7% of total cannabinoids have been reported. [1] [2]"

If this article is true than it is saying that Indica's have high THCV levels and thus could be blocking your CB1 receptor.




There 3/4 subspecies of Marijuana all marijuana is of the species 'Cannabis sativa L' but than you have 3/4 subspecies of the plant these are Sativa, Indica, Ruderalis and in some circles a 4th subspecies being Afghanica, but most refer to the Afghanicas as just plain Indica. So when you read Cannabis sativa L. ssp. indica the SSP stands for subspecies so in horticultural terms you have these: Cannabis sativa L. ssp. sativa, Cannabis sativa L. ssp. indica, Cannabis sativa L. ssp. ruderalis.

I hope you took notes, quiz tomorrow!!!
Click to expand...

actually, most of what i read says that sativas have a lot more of it. i'll find where i read that after work
 
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