You can use them without boosters, but I would recommend buying their big bud product, or a competitors PK booster product, they work very well, and are very reasonably priced.
The ratios to use should be right on the bottle, and they are on the advanced nutrients website. The veg ratio is I believe 1-1-1, and I can't remember what the flower is, but again, right on the website. People often use other ratios for 3 parts, look them up on here, they are all over the place. general hydroponics 3 part is essentially the same, so don't be afraid to duplicate the ratios you see on here from them. Would help to do a bit of research before asking these questions.