CBD a cure schizophrenia
- Thread starter LWD
- Start date
LWD
Active Member
What is ur diagnosis? I was on invega a couple years didn't make me itch but it gave me like permanent munchies and added 70lbs to my gut. I mean cbd may potentially dispel psychosis with virtually no side effects. That would kill competition of current available meds today.
LWD
Active Member
I am on latuda too, the lesser of all anti psychotic evils. Its side effects if I take it in the day are like depressed morbid t
houghts. That's why I take it at 3 am with a bowl of cereal and go directly back to bed so I don't have to endure the negative side effects. I did not know that about Cbd. I thought the high percentage in the smoke alone would be enough to mellow you out.
LWD
Active Member
I really hope CBd is the magic treatment cure for schizophrenia. I want to take something more natural than prescription meds. Once hemp fields in Washington and Colorado start producing then we may relatively quickly see CBd from hemp market shape up. I'd hate to be stuck on latuda my whole life. I am always looking for better ways to treat my scbizo
dirtnap411
Well-Known Member
blindbaby
Active Member
CAUSES this problem. not cures it. after all, the only time i talk to myself, is on weed. its not the wonder drug from heaven many claim. like everything, too much, or the wrong body chenistry, can be not so good. and now. to be insulted by a lib, for daring to qwesstion the godly one in the oval office, or in the pipe......lol. really, tho. too much of anything is no good.
ford442
Well-Known Member
marijuana can in no way cause schizophrenia - it is a hereditary disease meaning that one of your parents has to pass it down - like red hair and freckles... no amount of any drug that i know of can cause schizophrenia - there is methamphetamine induced psychosis - but, that is quite different...
LWD
Active Member
I got my illness induced from methamphetamine. So I'd probably be normal if I never would of taken it. But what's fucked up is my mom has schizophrenia in her family. So I am not sure what caused my illness. All I know is that I was fine before I started meth. I was on weed years before that it never did nothing but get me high. Scientists try to link cannabis as a cause of schizophrenia, well to some degree THC can induce psychosis in already schizo people. But cause a normal person to become a full blown schizophrenic, that has not and won't be proven. All the fed would like it to proven so to give another excuse to make marijuana illegal. Toking with a mental illness depends on your current stability I believe. There are people who are mentally ill on various different levels of stability. Some are slightly stable, and some are about to relapse. Well those people also give reports on what its like to be high with mental illness.. well if your already unstable and smoke of course your brain is sensitive and going to feel some effect from it. But I've smoked when I was stable on medication. I mean stable for years and from my experience marijuana did not cause me to relapse or hallucinate. In fact I hit some good indica and layed down felt like I was on a body roller coaster. Felt damn good. Now how can anyone say anything negative about medical marijuana need to get their facts straight. All marijuana is not considered equal or the same. THC/CBD ratios vary. Indica or Sativa. Yet ignorant people who classify it and say that ALL marijuana does the same thing as a whole, is not looking at it right. There's some indica that I could smoke and be peaceful on and there's probably some strain called Tahitian Terror, that would make me go paranoid out of my mind. Peace.
ford442
Well-Known Member
well.. schizophrenia lies dormant in childhood years - it comes on in men between like 18-24 and in women at more like 34-36 as i recall - so it comes on at a time in a young mans life where they have started to try some harder drugs and they get confused what is happening - i remember being a little weird as a kid - then when i took LSD it would hit me really harder than my friends sometimes.. later i took some meth and it wasn't long after than i started to have really bad symptoms - so, they say drugs can possibly bring on the problem more intensely, but you would still have the condition - i am glad that i was diagnosed - i think it would have been really worse living with non-exacerbated my entire life - instead i think it is good if you take some LSD and you react differently, then get diagnosed - simple as that..
GrowinTheDank
Active Member
This is not true whatsoever...
GrowinTheDank
Active Member
No, care to tell me how that would be relevant? Yes, I am schizophrenic. You should read elsewhere.
ford442
Well-Known Member
i have asked multiple doctors along the way and they all say that schizophrenia cannot come from external things. you would have some other condition then. i did not mean that your parents absolutely 100% have red hair and therefore you have 100% red hair - i mean that there has to be an underlying susceptibility to the condition is all. you cannot be tortured in a cell and develop schizo-anything to my knowledge. you get other things from being abused or psychologically traumatized mentally or physically.
i don't mean to be argumentative - i spent the morning yelling at clouds...
but, i have asked for example - 'doctor, could my condition have come from my use of LSD or meth?' and they say 'no, because you respond to anti-psychotic meds in the way you do, you do not have a condition brought on my wrong behavior, but rather a physiological predisposition' - like being born with three arms - i see it as a subtle physical difference in the growth of the brain. physical abuse by chemicals would go away - schizophrenia does not.
again, i want to just have a nice holiday here, let's say we are probably both wrong - unless you have a different theory? what do i need to read elsewhere? i have googled my brains out in the past. evidence says that i will have this condition from the moment i am born to the moment i die.
i don't mean to be argumentative - i spent the morning yelling at clouds...
but, i have asked for example - 'doctor, could my condition have come from my use of LSD or meth?' and they say 'no, because you respond to anti-psychotic meds in the way you do, you do not have a condition brought on my wrong behavior, but rather a physiological predisposition' - like being born with three arms - i see it as a subtle physical difference in the growth of the brain. physical abuse by chemicals would go away - schizophrenia does not.again, i want to just have a nice holiday here, let's say we are probably both wrong - unless you have a different theory? what do i need to read elsewhere? i have googled my brains out in the past. evidence says that i will have this condition from the moment i am born to the moment i die.
OGEvilgenius
Well-Known Member
It's not known what causes schizophrenia. What is known is that the diagnosis rates have remained unchanged (statistically significantly anyway) over the past 100 years or so. Cannabis use has increased during this period. There appears to be no direct and obvious link, although I would suggest any drug that alters your brain chemistry significantly probably can increase your chances of having your first episode. There is evidence that it runs in families, I don't believe the gene has been isolated (and just because there's a gene of course doesn't mean there aren't external causes, the gene could simply make you more predisposed to those causes). It's not a well understood disease, but high CBD seems like it would be potentially very effective and I have personally been really curious to see how a schizophrenic would react to a high CBD concentrate - something to deliver a really strong dose anyway, maybe edibles.
ford442
Well-Known Member
[h=1]http://psychcentral.com/news/2012/06/07/marijuana-compound-may-beat-antipsychotics-at-treating-schizophrenia/39803.html
Marijuana Compound May Beat Antipsychotics at Treating Schizophrenia[/h]
A certain marijuana compound known as cannabidiol (CBD) can treat schizophrenia as well as antipsychotic drugs, with far fewer side effects, according to a preliminary clinical trial. The research team, led by Markus Leweke of the University of Cologne in Germany, studied 39 people with schizophrenia who were hospitalized for a psychotic episode. Nineteen patients were treated with amisulpride, an antipsychotic medication that is not approved in the U.S., but is similar to other approved drugs.
The remaining 20 patients were given CBD, a substance found in marijuana that is considered responsible for the mellowing or anxiety-reducing effects. Unlike the main ingredient in marijuana, THC, which can trigger psychotic episodes and worsen schizophrenia, CBD has antipsychotic effects, according to prior research in both animals and humans.
Neither the patients nor the scientists knew who was receiving which drug. At the end of the four-week trial, both groups made significant clinical improvements in their schizophrenic symptoms, and there was no difference between those getting CBD or amisulpride.
“The results were amazing,” said Daniel Piomelli, Ph.D., professor of pharmacology at the University of California-Irvine and a co-author of the study. “Not only was [CBD] as effective as standard antipsychotics, but it was also essentially free of the typical side effects seen with antipsychotic drugs.”
Antipsychotic drugs may cause devastating and sometimes permanent movement disorders; they can also lower a patient’s motivation and pleasure. The new generation of these drugs can also lead to weight gain and increase the risk for diabetes. These side effects are well known as a major hindrance during treatment.
In the German study, weight gain and movement problems were observed in patients taking amisulpride, but not CBD.
“These exciting findings should stimulate a great deal of research,” said Dr. John Krystal, chair of psychiatry at Yale University School of Medicine, who was not associated with the research. He notes that CBD not only had fewer side effects, but also seemed to work better on schizophrenia’s so-called “negative symptoms,” which are notoriously hard to treat.
Negative symptoms of schizophrenia include social withdrawal, a lowered sense of pleasure and a lack of motivation. However, since current antipsychotic medications can actually cause these negative symptoms, it wasn’t clear whether CBD was better than amisulpride at getting rid of these symptoms, or whether CBD simply caused fewer side effects to begin with.
If replicated, the results suggest that CBD may be at least as effective as current medications for the treatment of schizophrenia, without the severe side effects that make patients reluctant to take medication.
“The real problem with CBD is that it’s hard to develop for a variety of silly reasons,” said Piomelli. Since it comes from marijuana, there are obvious political issues surrounding its use. Extracting it from the plant is also expensive.
But the biggest obstacle may be that CBD is a natural compound, and therefore can’t be patented the way new drugs are. So although CBD could outsell the current blockbuster antipsychotic drugs, pharmaceutical companies aren’t likely to develop it. Researchers are working to develop synthetic versions of CBD that would avoid such hurdles.
“We have one and are hoping to move forward in the near future,” Piomelli said.
Marijuana Compound May Beat Antipsychotics at Treating Schizophrenia[/h]
A certain marijuana compound known as cannabidiol (CBD) can treat schizophrenia as well as antipsychotic drugs, with far fewer side effects, according to a preliminary clinical trial. The research team, led by Markus Leweke of the University of Cologne in Germany, studied 39 people with schizophrenia who were hospitalized for a psychotic episode. Nineteen patients were treated with amisulpride, an antipsychotic medication that is not approved in the U.S., but is similar to other approved drugs.
The remaining 20 patients were given CBD, a substance found in marijuana that is considered responsible for the mellowing or anxiety-reducing effects. Unlike the main ingredient in marijuana, THC, which can trigger psychotic episodes and worsen schizophrenia, CBD has antipsychotic effects, according to prior research in both animals and humans.
Neither the patients nor the scientists knew who was receiving which drug. At the end of the four-week trial, both groups made significant clinical improvements in their schizophrenic symptoms, and there was no difference between those getting CBD or amisulpride.
“The results were amazing,” said Daniel Piomelli, Ph.D., professor of pharmacology at the University of California-Irvine and a co-author of the study. “Not only was [CBD] as effective as standard antipsychotics, but it was also essentially free of the typical side effects seen with antipsychotic drugs.”
Antipsychotic drugs may cause devastating and sometimes permanent movement disorders; they can also lower a patient’s motivation and pleasure. The new generation of these drugs can also lead to weight gain and increase the risk for diabetes. These side effects are well known as a major hindrance during treatment.
In the German study, weight gain and movement problems were observed in patients taking amisulpride, but not CBD.
“These exciting findings should stimulate a great deal of research,” said Dr. John Krystal, chair of psychiatry at Yale University School of Medicine, who was not associated with the research. He notes that CBD not only had fewer side effects, but also seemed to work better on schizophrenia’s so-called “negative symptoms,” which are notoriously hard to treat.
Negative symptoms of schizophrenia include social withdrawal, a lowered sense of pleasure and a lack of motivation. However, since current antipsychotic medications can actually cause these negative symptoms, it wasn’t clear whether CBD was better than amisulpride at getting rid of these symptoms, or whether CBD simply caused fewer side effects to begin with.
If replicated, the results suggest that CBD may be at least as effective as current medications for the treatment of schizophrenia, without the severe side effects that make patients reluctant to take medication.
“The real problem with CBD is that it’s hard to develop for a variety of silly reasons,” said Piomelli. Since it comes from marijuana, there are obvious political issues surrounding its use. Extracting it from the plant is also expensive.
But the biggest obstacle may be that CBD is a natural compound, and therefore can’t be patented the way new drugs are. So although CBD could outsell the current blockbuster antipsychotic drugs, pharmaceutical companies aren’t likely to develop it. Researchers are working to develop synthetic versions of CBD that would avoid such hurdles.
“We have one and are hoping to move forward in the near future,” Piomelli said.
Jogro
Well-Known Member
First of all schizophrenia isn't a purely genetic disease. The etiology isn't established, but its fairly clear based on statistical analysis that the cause has both genetic and environmental components.
Cannabis use is most definitely LINKED to schizophrenia.
Whether or not the drug CAUSES the disease is debatable. It may be that the drug increases expression of disease in people already genetically pre-disposed, or may even be that people genetically susceptible to schizophrenia are more likely to gravitate towards using cannabis (perhaps as a form of self-medication, perhaps not).
But I think what can be said, with a pretty high degree of certainty, is that CBD (which is a naturally occurring compound) cannot CURE schizophrenia. CBD-rich hash has been around for literally thousands of years, and plenty of schizophrenic patients have used/smoked it in that time. If the stuff could cure schizophrenia, this would be well-established by now.
I'd even go so far as to say that if its an effective symptom reducer, that would probably be known by now too, but I won't entirely dismiss the possibility out of hand.