I once had the pleasure of starting a grow of the same strain at the exact same time, to the day, as another person on a different forum.
He had a very similar setup, 600w hps cooltube, 2x4, hydro. He religiously removed every fan leaf that popped up all throughout the plant's life. In the end, his plant took an extra month in veg, an extra month in flower, and it produced half the weight mine did.
Two extra months, half the weight. At that point I decided defoliation was retarded.
Granted, he could have fucked up anything else over the course of the grow, if he did he didn't mention it. The only difference that he admitted to was butchering the plant. I posted a message at the end telling him my results and asking him if he learned anything and asked if he was going to continue defoliating. IIRC he said he would continue to fully butcher the plants. I didn't think me just telling him my results, telling him that I did so much better than him (and I didn't even do that good), would convince him (I didn't do a journal or pics or anything). I didn't really care if it convinced him to stop because it didn't matter if he learned from his own mistake or not, I did learn from his mistake. I got to witness first hand how terrible defoliating is. I did thank him for that.