I like to smoke while drinking, it calms me down when I get really drunk and stops me from mouthing off like I seem to do on occasion. I think mixing beer/wine or wine/spirits makes for a much nastier hangover than pot ever could. I also really recommend you don't ever take LSD and MDMA together. For three days after "candy flipping" I was a pale, depressed, sack of shit. I wont be doing that again...