Those are two completely different thing.
Never did acid but I'd say for ex depends on how much ya do,
There was a couple weekends on ex and beer and no sleep but on the normal occasion take 2-3 pills in one night
At those times I'd usually be up till the next night finally get some sleep and feel like blah the next day. Just feel shitty really wouldn't want to work or have to do anything for that matter.
But after a good day of vegging some food and another nights rest your good to go. I always hated the feeling the next day.