that's enough air movement if all you are doing is exchanging oxygen rich air with fresh outdoor air. if you need to bring in air to cool the room, you need alot more air.
on the question of lights you're kinda asking how fast you should drive without telling us what road you're on.
before you grow you need to know:
how much weed are you trying to grow (eg 1 pound/4 months)
how many plants does that take (eg 4 ounces per plant)
how much space does one plant take (eg 3 square feet per plant)
how much light to cover 12 square feet (eg 7000 lumens per square foot)
look up how big a light to produce 84,000 lumens - 600 watt hps
see that it takes only a small portion of your room to grow one pound (12 square feet out of 100 square feet) with the assumptions i made. use your own assumptions on total yield, yield per plant and size of plant to plan your grow room.
most people with that much room would divide it into veg and flowering areas so you can produce perpetual harvests.