Freebase

Jakabok Botch

Well-Known Member
hey everyone....quick qt....what is freebase??? iv asked this qt several times but never get a straight answer....thx for all help
 
k fuck you too....now is that a liquid-a powder-a rock-fuckin metal??? if i make it should i expect to shoot up or smoke....u no this isnt the worse qt iv seen on here...but glad when iv got a qt its all fuckin snot-nosed remarks...or nothin at all...really makes me want to stay here and help the rest...if ur just goin to be a prick about it just pass over my thread....
 
Not being a prick your being an idiot, what drug are you trying to free base?


Freebase or free base refers to the pure basic form of an amine, as opposed to its salt form. The amine is usually an alkaloid natural product. Free base is commonly used in chemistry and pharmaceuticals to describe the unprotonated amine form of a compound.

Most alkaloids are unstable in their pure form and are often stored as salts. The salts usually exhibit greater water solubility. Common counterions include chloride, bromide, acetate and oxalate. Because of the ubiquity of chloride salts, formed from the reaction of the amine with hydrochloric acid, these amine derivatives are known as the hydrochlorides. For example, compare the free base hydroxylamine (NH2OH) with hydroxylamine hydrochloride (NH3OH+ Cl-).

The term "freebasing" refers to a method of deprotonating the common hydrochloride salt form of cocaine sold as a street drug to prepare it for smoking. The process can also remove inactive adulterants. The free base is preferred for smoking because the evaporation point of the free base is further apart from the burning point compared to the hydrochloride salt, making the salt form more prone to destruction by pyrolysis. Some of the active drug is lost in the deprotonation process. Freebasing became popular in the United States during the 1980s, mainly due to the fear of diseases such as HIV and viral hepatitis, since users did not have to share hypodermic needles.[1]
[edit] References


edit: nvm
 
Depends, freebase of what?

Freebase cocaine- sure you can smoke it, probably wouldn't want to bang it.
Freebase heroin- smokable, bangable.
Freebase MDMA- Probably caustic.
Freebase is really only a term when the appropriate molecule is referred too.

Anytime someone is talking freebase, its usually cocaine, and its almost always a solid. Although an oil at higher temperatures.
 
yes...iv read it...i did try google before askin u(my biggest mistake)... guess im just too fucking stupid to gather all my info from that....but nyways just forget it....ill gather my info elsewhere
 
i think the problem here is the fact that jakabok has NO IDEA what chemistry is...

freebase = the state of the material (for the laymen) so if you have a bottle of cough syrup that has dxm hbr it isnt freebase dxm but the salt state of it ...
 
Or are we talking about freebase methaqualone? It turns to a hydrochloride once it hits the stomach but the effect lasts much longer and it seems stronger. Of course considering that there is more of the chemical and less of the "salt" I suppose it would be stronger. By what? about 12 percent or so? Say, does anyone know how to turn methaqualone hydrochloride into a free base?
 
Allow me to explain this to you in media ... and neutralize the hostilities ...
Lets at least try to get along ...OP is new ... he might turn out to be
a swell DUDE !

[video=youtube;ocpuuaNwMSw]http://www.youtube.com/watch?v=ocpuuaNwMSw&feature=related[/video]

(Had to do it ... U know me and Holes ... can't get enough)

:)
 
In pretty much every drug you have a nitrogen atom as part of the molecule. In an acidic enviroment this atom will get protonated, causing the molecule to get a positive charge. It will then form a salt with a negatively charged ion (the anion of the acid). So hydrochloric acid will for the hydrochloride salt, sulfuric acid the sulfate salt, etc. The freebase is just the nonprotonated molecule, which is called a base because it will bond with a proton from an acid. Freebase drugs typically vaporize more readily than salt forms and are better for smoking, but are usually not water soluble enough to dissolve a dose for injection in neutral water. They will dissolve readily in an acidic solution.

@Ellis Dee you can't inject freebase heroin without dissolving it in acid, and the same process can be used to make freebase coke injectable.
 
From what I understand heroin very quickly deprotonates in the bloodstream, its just the freebase doesn't dissolve in water readily so its hard to get an injectable solution.

Sure you could dissolve them in an acid, but they wouldn't rightly be freebase molecules anymore. :D
 
Never ever ever inject lemon juice. It leads to all kinds of infections. Instead use citric acid or ascorbic acid or white vinegar to dissolve freebases in water. My veins hurt just thinking about that.
@Ellis heroin doesn't deprotonate in the body (it doesn't even have an acidic proton, an alkoxide or something with a similar pKb might be able to grab one of the protons on the 7,8 double bond or the one on the stereo center next to it or one off the aromatic ring, but that's lab conditions and would probably destroy the molecule anyway), the acetyl groups hydrolyze to form 6-monoacetyl morphine and then morphine. The base will not dissolve in water without an acid.
 
Yeah I know, what I am referring to 'deprotonating' is the counter ion from the base. Morphine doesn't hit the receptor otherwise!!

And there is more than water for making solutions!!
 
U dudes are the best !
Lets see some data !!

bitches_love_chemistry_by_rider424-d3da8fg.jpg
 
I won't be deluging you with my resources. But just think.

Certainly there are benzo's that can be injected with the correct 'solvent', thats all we require. And the freebasing of molecules in the body is necessary for their action. Salts just change solubility, and in so doing, changes their perceived effects and effectiveness.

Salts are useful when one doesn't like needles.
 
It is not about ME ... it is about collective research we can PiN to this thread ....
SO others might read the data ..and UNDERSTAND.

Your words ... and thoughts will live forever .... realize.

Understanding FreeBase (For Chimps ... who don't understand how to freebase 2 GOOD)

;)
 
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