Checking the trichomes with a 60x loupe is the best way to get a perfect harvest.
When they are cloudy is at the optimal peak of THC, when they start to turn red, then THC starts to degrade. You want most of the plant to be cloudy, with a few turning red. I know there are some growers who believe in the double harvest, where they chop the top colas first, then wait another week before chopping the lower buds, as the lower buds tend to mature slower due to light penetration.