The Future Simulation Postulation™ is a tempting hypothesis because it really only requires one assumption, and once you make that assumption the likelihood that we are in a simulation becomes near certain. However, that one assumption is huge. Occam's razor is not just about counting the number of assumptions, but the size as well. For us to be in a simulation we have to assume that one day humans will discover a source of computing power that will allow us to simulate reality to the degree that we experience it. Further, the computing power would need to be such that each simulation is capable of itself running its own simulations. That's a fantastic amount of processing. However, if this indeed were the case, we could have potentially millions of simulations each running their own millions of simulations, in which case the odds that we ourselves are in one of those simulations is quite likely.
It's easy to waive our hands and say, oh well, it's the future after all, and computing power continues to grow by leaps and bounds, and quantum computing is on the way, and bla bla. Maybe that's all true, but that still doesn't justify the assumption. We could wipe ourselves out before we ever get to that point, or it may be that the computing power necessary would be more than the universe could ever supply. So although I think it is an extremely interesting situation to think about, to me it's still doesn't offer any more merit than "god did it."
Even more so, if we were in a simulation and could know it, I don't see how it would really help other than satisfying curiosity. Life as we know it wouldn't really change. It wouldn't offer any sort of path to transcendence, or give us any sort of advantage over the simulation. I suppose it might convert a few theist into atheists, but I think most people would just keep believing as they please.
