I think you're asking how to separate the buds before you sit down to enjoy a smoke. Uh... technique varies but basically just rip it apart, take out all stems/seeds, and enjoy? Don't turn it into dust now, leave the "flowers and leaves" whole.... hell I don't know, you just do it!
If you mean break it up for smaller storage purposes, its really up to your discretion. Storage of it is where you must be careful in order to maintain freshness.