LST and pruning

When you LST train a plant , should you also defoliate and prune some of the shorter mini shoots that pop out from the lower horizontal trained branches? My girls are 45 days old and will be flipped in 2 weeks.

If you need some info:

2 plants. Granddaddy purple, Pineapple Express both fem both photoperiods, both very healthy and happy.

light: MH TS1000 Veg MHTSW2000 for Flower (goal is 3-4 oz)

tent: 2.3 x 2.3 x 5.2 MH

temp: 78F RH 55%

Here are the latest pics of em if that helps.

I personally don't cut leaves when I LST. I will usually LST quite often and I will only trim lower branches/leaves 2-4 times during the life cycle, depending on the plant. I just wait until it really needs it and then do quite a bit of trimming on the lower foliage.
There's nothing wrong with doing them at the same time, just don't trim leaves and branches every time you LST. Plants need very little if any time to recover from LST but they will want 24-48 hours to recover after some chopping. If you were to trim up branches and leaves too many times you could potentially lose weeks of good growth.

I don’t touch them for 3-4 days after I defoliate and trim them. And I water and or feed them the same day I do this as well to reduce the stress of the trimming job they went through. I have good ventilation in my tent but even if I didn’t trim or defoliate at all I think I would increase the chance of getting powdery mildew which I do not want at all. Yea unless the bigger fans leaves are covering potential bud sites I leave them alone and just do the bottom and middle of the canopy. I always use sterilized trimmers if your wondering as well.