Possible to change soil?

My soil doesn't have perllite in it and I should have done that plus I found some new better soil......My plants look droopy and I think the soil they are in is wack so is it possible to change them over into new soil without f'ing up my girls? they are about a week or two from flower time and in soil obviously.....HELP!
 

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You can transplant your ladies into new soil, won't hurt them. Just be careful when handling the rootball
 
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