ive been in soil an hyrdro. nft, dwc, an flood n drain, it all comes down to experiance. do some research on what you want like do you want tall plants with massive yields but longer veg or alota plants turning over more quickly. me personaly, i run a sog of 48 cutting once a month n get about 1.5 lbs a month. i veg for about 2 weeks, an in each system i got comparable results as the last i used. imo flood drain is easy to use u dont need to worry about an air pump in you rez, or getting root rot (unless you use rockwool n flood 5 times a day)