I have never run more then 3 strains at the same time and this is my first time growing 4 out of the 5 strains i have and also the first time i used this particular bucket system so I'm not too sure what to expect. If all goes well and my plants average out at least moderate yielders (critical kush and death star are heavy producers, GSC is known to be more scarce weight) I am hoping for at least 28oz of high quality medication for my patients. Also the reason for growing 5 strains is so i can see what strain(s) treat their symptoms most effectively and work best for them.