I normally cut off all the bigger leaves and leave the sugar smaller leaves then hang upside down in one piece , I have split plants up it all depends how much prep I put into it before actually chopping them down if I don't trim the big leaves off before harvest I'll do it in sections but if I do all the prep it's cut and hang in one
you could hang the plants whole and get a swivel chair to sit on and manicure the leaves off while there upside down you won't be bending over as much but looking up which might aggravate your neck
I think for mould to grow it has to be a certain enviroment and if you avoid that and dry at the right range you shouldn't have a problem