Holy moly; got too much stuff to possibly remember in one post, but here goes my best...........
1) You're gonna need to get to the other side of each of your flowering tables, so the corners won't work - truthfully, not sure that two 4' tables work in a 10' room - I have the same 10' requirement, and I'm planning to do 3x3 tables, just to be able to leave room around them to work.
2) Having a water source in or near your grow is VITALLY important - I understand you're in shape and don't mind lugging water around, but trust me, that's gonna get real old, real quick. Real quick. BTW, you say that you're going to have two reservoirs in your flower room - how are you going to get the water to them? And have you ever used an R/O system? Not asking that to be a smartass, but I personally had no idea how they worked before I got one - basically, you need a reservoir (drain would be better, but I doubt you have a sink in your bedroom) just to catch the "waste" water, and another to catch the "clean" water - the kicker is, there's about 4X as much waste water produced as clean water.
BTW, if buying plastic trash cans, don't be a moron like me and get one with wheels on it (they tip over). Also, I'd recommend buying two and doubling them up.
3) Not related to your blueprints design, but while I remember it - you should really invest in some calibration solution and learn to calibrate your own meter. In a month the meter can be off by .5+, and what happens if you come home one night and your plants are dying on you? The store's not open, so your buddy can't do it, and then you don't know what you're dealing with............it's cheap and simple, and it's really a necessity, IMHO.
4) I'm assuming the house has central AC in addition to the window ACs that you're going to be running? Because if not, those ACs won't make a lick of difference - even if it does have central AC, those ACs are way undersized for what you need. You always wanna go bigger so the AC doesn't have to run as much - I'd say more like 12BTU for the veg and 14-18BTU for the flower, but someone can correct me if my sizing is off (haven't run a window AC in a long time, in full disclosure).
5) You don't "need" exhaust and intake for your veg room, but it will slow your plants down - without fresh air, the CO2 will drop to ~200PPM and just chill there, which means that your plants are only growing about 55% as quickly as they could if they had an atmosphere of ~350PPMs. Not killer, but something to think about - if you get a big enough AC for in there, I'd just run a propane generator in both rooms - I have one (although currently using bottles right now), but generators are the shit for efficiency - would last you months on one tank of propane.
6) I know you have people telling you that dirt/soil less is the way to go, but that's really, really, really bad info, IMHO - for the amount of weed you're planning on growing, that amount of dirt medium is just not very practical, and just like the lugging water, you're going to get very, very tired of it. I'd HIGHLY recommend just starting out with a hydro system (which if memory serves you plan on upgrading to anyways), so as not to waste any money or time buying "dirt accessories" - it's a more efficient and faster way to grow, period.
Just trust me, buy some flood tables and some hydroton/rockwool and call it a fucking day - no mess, no fuss, and it's as easy as growing in dirt. Okay, done preaching about that.
7) Not sure how tall your moms are gonna be, but I'd be shocked if you could fit 12 18" clones and 4 bushy mothers under a 1K - you're going to need to rethink that lighting setup. Firstly, assuming the moms will be fairly taller, they're going to shade the shit outta the clones - I'd really recommend having the moms under one light and the clones under another. 4 moms would be fine a 400, and leave the 12 clones to have the 1000 to themselves.
For your flower room, how are you planning on pulling air from the outside for your 10" fan? You're obviously aware that ducting coming out of a window arouses suspicion, so what's your plan for that? In terms of keeping all four lights cool, I can't comment with any authority on that, other then to say you're not "supposed" to cool more then two lights in succession off of one fan - I'd guess that the third and fourth lights in that sequence won't be getting nearly as cool as the first two, but someone else could either confirm or deny that suspicion.
9) Again with the CO2 tanks - don't mess with them, get a generator. For a room your size, you'll be going through multiple tanks per week - just like water, gets real old, real fast lugging them to and from the welding supply store.
10) In terms of your question regarding where the R/O setup is kept, it's gotta be at your water source, wherever that may be.
11) I know I said I was done preaching, BUT YOU'RE BUILDING TABLES FOR YOUR FLOWERING PLANTS ANYWAY!!!! Just throw a pump and a reservoir under each table, and put your watering wand and pallets of dirt on craigslist.
That's all I've got for now, good luck.
