You don't...a mutation is a mutation. While some mutations occur at different levels (genome, chromosome, gene), each mutation in it self is different than the last. And as hard as it is to believe anything good can come from a mutation (statistics are completely on your side), that is the basis of the theory of evolution. Although I believe evolution is much less random than we think (adaptation). Either way, inducing mutation is actually a form of plant breeding widely practiced. Shoot the plants with some x-rays, or dip them in carcinogenic chemicals, and hope for the best. The only reason a mutated plant would be hard to clone is if something in the genotype was changed that directly effected the rooting process...which is hard to believe is linked with potency. Just my 2 cents...