I'm thinking of trying a few different autos outdoors next year. The CO outdoor season is not particularly good for cannabis, in addition to the summer heat and wind, by the time the nights are long enough to induce flowering, the frosts are never far behind. Snow as early as September is not super unusual. The only real way I've ever been able to get good results outdoors in this state was by just moving plants that were vegged and induced artificially outdoors as soon as the nights are long enough. Not that there aren't plenty of people growing outdoors here, but the quality is almost always exceptionally low. If you were growing an auto, you could reliably get 1-2 harvests outdoors every year; which is something I think a lot of CO growers would be into.
That said, the potency remains a concern, and a lot of the autos that are currently available are available as feminized beans, which would prevent people from simply letting their autos going to seed for the purposes of reproduction. Potency is not really as much of a concern as is the quality of the high, as I love making extracts, and extracts are much more dependent on the quality of the cannabinoid/terpene blend than the actual percentages of the plant, I'm going to be composting all the actual plant matter anyways. I'm currently thinking of just picking up two packs of Lowryder regs to start next spring, and then working some of the better autoflowering male pollen into my biggest and beastliest female cuts for an f1 generation, and then using the autoflowering males and females to produce a great quality of mostly autoflowering (hopefully) f2 beans. I'm an anticorporate anarchist asshole, so I'd love to drop a few hundred beans to give away with purchase at a shop so that people could steadily produce their own colorado-outdoor-viable seeds.