Well the normal dose to enter a k-hole is 500mg, your LD50 for ketamine is quite a bit higher than that (many times that dose) LD50, 224±4 mg/kg (adult mice). LD50, 229±5 mg/kg (rats), that means if you weigh 110 pounds, you would need 10,000mg to die. (minimally)
So, do not let your friends...