Most pressure cookers are set at 15 lbs. The little weight (or spring) is set to release slightly when the pressure gets more than that so you are limited. Sterilizers (autoclaves) will go higher - and they retain a vaccuum after the fact so that they can be opened in a sterile space after they have cooled. I believe autoclaves can go up to 18 or 20 lbs.
Temperature is always the same - well, sort of - if the pressure is the same - talk to some Boyle's law experts on this I could be way wrong in the theory. Point is though, if that weight is bobbling, you are at about 15 lbs and what ever temperature that corresponds to.
Higher than 230 or 250 and you begin to caramelize your substrate - mushrooms don't like caramel.
Any wet temperature at boiling will eventually kill almost all endospores. But the presumption is that the temperature is wet and everywhere the same, endospores can survive in tiny places in your substrate for quite some time. Now endospores are grown with a tough shell that will resist very high heats for very long periods of time. All it takes is for a single spore to survive in your substrate and you are done. Considering that there may be many thousands or tens of thousands in your jar, even though your heat treatment kills 99.9 percent of them in the first 20 minutes of sterilization, it is those last few resistant ones that you are gunning for.
The best possible trick is to get those endospores to come out of their shells - offer them an ideal environment and let them live just a little while and then your sterilization will work much better. Of course, too long and you will begin to alter the ph of your substrate making it less desireable for your target organism.