could it also be a heat / humidity issue ? (even with the fans ) due to you having to heat your house for winter.
i have a hi/low recall thermostat that i got on ebay for like 15 bucks....
"Both of these leaves in figure 3 and figure 4 are from the same plant. It could be over fertilization, but more likely it is due to the pH being off. Too high or too low a pH can lock up nutrients in the form of undisolvable salts and compounds, some of which are actually toxic to the plants. What then happens is the grower then tries to supplement the plants diet by adding more fertilizers, throwing off the pH even more and locking up even more nutrients. This type of problem is seen more often in soil mixes, where inconsistent mixing of the medium's components leads to "hot" spots."
the pics below this passage look similar to yours !!
and also:
http://www.icmag.com/ic/showthread.php?t=11688
" Solution to fixing a Manganese deficiency
Foliar feed with any chemical fertilizer containing Mn., or mix with water and water your plants with it. Any Chemical/Organic nutrients that have Manganese in them will fix a Manganese deficiency. (Only mixing at ½ strength when using chemical nutrients or it will cause nutrient burn!) Other nutrients that have Manganese in them are: Manganese chelate, Manganese carbonate, Manganese chloride, Manganese dioxide, Manganese oxide, Manganese sulfate, which are all fast absorption. Garden Manure, Greenssand are both good sources of manganese and are medium/ slow absorption.
Now if you added to much chemical nutrients and or organics,( which is hard to burn your plants when using organics) You need to Flush the soil with plain water. You need to use 2 times as much water as the size of the pot, for example: If you have a 5 gallon pot and need to flush it, you need to use 10 gallons of water to rinse out the soil good enough to get rid of excessive nutrients.
Picture 1 shows a manganese deficiency in flowering."
this picture looks even more like yours !!
It's probably a combo of these things but it all starts with mixing the diff soils together incorrectly !! I know that you won't be mixing soils again, lol !!
can flushing numerous times compensate ? I don't know !! obviously this late in the game transplanting is not gonna happen. If you flush again and don't see improvement quickly it's time to harvest early before you lose the harvest altogether !! You are definitely more experienced than I am but I don't think that i'm that far off !!
Peace again,
Bill