if you don't go to sleep before you take them on saturday you will be fine, i have found in my life of drug use that sleeping is what builds tollarance, your body uses sleep to heal and therfore learn to tollerate and expell toxins. so if you just redose a couple times you wont need to sleep anyway.
but you will look like crap from the sleep depervation...skin all oily, bags under the bloodshot eyes and weekness from not eating(whenever i take things i never want to eat)... you wont want to go see some chicks or go clubbing durring this period.
peace
-Cult