After seeing this:
http://www.nytimes.com/2009/04/26/magazine/26drugs-t.html?_r=1
and this:
http://www.foxnews.com/story/0,2933,464484,00.html
I think its safe to say... there is no BEST way. You just need to make sure you cover every angle. Don't drive high, thats what really grinds my gears...